Predictive genomic markers of response to VEGF targeted therapy in metastatic renal cell carcinoma.

Predictive genomic markers of response to VEGF targeted therapy in metastatic renal cell carcinoma.

BACKGROUND:First-line treatment for metastatic renal cell carcinoma (mRCC) is rapidly changing. It currently includes VEGF targeted therapies (TT), multi-target tyrosine kinase inhibitors (TKIs), mTOR inhibitors, and immunotherapy. To optimize outcomes for individual patients, genomic markers of res...

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Bibliographic Details
Main Authors: David D Stenehjem, Andrew W Hahn, David M Gill, Daniel Albertson, Banumathy Gowrishankar, Joseph Merriman, Archana M Agarwal, Venkata Thodima, Erik B Harrington, Trang H Au, Benjamin L Maughan, Jane Houldsworth, Sumanta K Pal, Neeraj Agarwal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210415

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https://doi.org/10.1371/journal.pone.0210415

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