Key regulatory oxysterols in liver: analysis as Δ4-3-ketone derivatives by HPLC and response to physiological perturbations

Key regulatory oxysterols in liver: analysis as Δ4-3-ketone derivatives by HPLC and response to physiological perturbations

A number of oxysterols have been implicated in metabolic regulation. Key among these are (24S),25-epoxycholesterol and (24S)-hydroxycholesterol, high affinity ligands for the nuclear transcription factor liver X receptor α; 27-hydroxycholesterol, a bile acid synthetic intermediate; and 25-hydroxycho...

Full description

Bibliographic Details
Main Authors: Zhe Zhang, Dansu Li, Daniel E. Blanchard, Steven R. Lear, Sandra K. Erickson, Thomas A. Spencer
Format: Article
Language:English
Published: Elsevier 2001-04-01
Series:Journal of Lipid Research
Subjects:
(24S),25-epoxycholesterol
(24S)-hydroxycholesterol
25-hydroxycholesterol
27-hydroxycholesterol
synthesis
HPLC analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520303849

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520303849

Similar Items