Key regulatory oxysterols in liver: analysis as Δ4-3-ketone derivatives by HPLC and response to physiological perturbations

Key regulatory oxysterols in liver: analysis as Δ4-3-ketone derivatives by HPLC and response to physiological perturbations

A number of oxysterols have been implicated in metabolic regulation. Key among these are (24S),25-epoxycholesterol and (24S)-hydroxycholesterol, high affinity ligands for the nuclear transcription factor liver X receptor α; 27-hydroxycholesterol, a bile acid synthetic intermediate; and 25-hydroxycho...

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Bibliographic Details
Main Authors:	Zhe Zhang, Dansu Li, Daniel E. Blanchard, Steven R. Lear, Sandra K. Erickson, Thomas A. Spencer
Format:	Article
Language:	English
Published:	Elsevier 2001-04-01
Series:	Journal of Lipid Research
Subjects:	(24S),25-epoxycholesterol (24S)-hydroxycholesterol 25-hydroxycholesterol 27-hydroxycholesterol synthesis HPLC analysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520303849

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