Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth.

Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth.

Preventing pathological ocular angiogenesis is key to treating retinopathy of prematurity, diabetic retinopathy and age-related macular degeneration. At present there is no small molecule drug on the market to target this process and hence there is a pressing need for developing novel small molecule...

Full description

Bibliographic Details
Main Authors: Halesha D Basavarajappa, Bit Lee, Xiang Fei, Daesung Lim, Breedge Callaghan, Julie A Mund, Jamie Case, Gangaraju Rajashekhar, Seung-Yong Seo, Timothy W Corson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994091?pdf=render

Internet

http://europepmc.org/articles/PMC3994091?pdf=render

Similar Items