Bone Marrow Mesenchymal Stromal Cell-Derived Periostin Promotes B-ALL Progression by Modulating CCL2 in Leukemia Cells

Summary: Periostin (POSTN) is a multifunctional extracellular component that regulates cell-matrix interactions and cell-cell crosstalk. POSTN deletion significantly decreases leukemia burden in mice; however, the underlying mechanisms by which POSTN promotes B cell acute lymphoblastic leukemia (B-A...

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Bibliographic Details
Main Authors: Zhenling Ma, Xueli Zhao, Mingjiao Deng, Zhengjie Huang, Jing Wang, Yi Wu, Dan Cui, Yingfu Liu, Rushi Liu, Gaoliang Ouyang
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719300439