Non-instrumented incubation of a recombinase polymerase amplification assay for the rapid and sensitive detection of proviral HIV-1 DNA.

Non-instrumented incubation of a recombinase polymerase amplification assay for the rapid and sensitive detection of proviral HIV-1 DNA.

Sensitive diagnostic tests for infectious diseases often employ nucleic acid amplification technologies (NAATs). However, most NAAT assays, including many isothermal amplification methods, require power-dependent instrumentation for incubation. For use in low resource settings (LRS), diagnostics tha...

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Bibliographic Details
Main Authors: Lorraine Lillis, Dara Lehman, Mitra C Singhal, Jason Cantera, Jered Singleton, Paul Labarre, Anthony Toyama, Olaf Piepenburg, Mathew Parker, Robert Wood, Julie Overbaugh, David S Boyle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4180440?pdf=render

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http://europepmc.org/articles/PMC4180440?pdf=render

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