Chemical intervention of influenza virus mRNA nuclear export.

Influenza A viruses are human pathogens with limited therapeutic options. Therefore, it is crucial to devise strategies for the identification of new classes of antiviral medications. The influenza A virus genome is constituted of 8 RNA segments. Two of these viral RNAs are transcribed into mRNAs th...

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Bibliographic Details
Main Authors: Matthew Esparza, Amir Mor, Hanspeter Niederstrasser, Kris White, Alexander White, Ke Zhang, Shengyan Gao, Juan Wang, Jue Liang, Sei Sho, Ramanavelan Sakthivel, Adwait A Sathe, Chao Xing, Raquel Muñoz-Moreno, Jerry W Shay, Adolfo García-Sastre, Joseph Ready, Bruce Posner, Beatriz M A Fontoura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008407