Evaluating the Anti-cancer Efficacy of a Synthetic Curcumin Analog on Human Melanoma Cells and Its Interaction with Standard Chemotherapeutics

Evaluating the Anti-cancer Efficacy of a Synthetic Curcumin Analog on Human Melanoma Cells and Its Interaction with Standard Chemotherapeutics

Melanoma is the leading cause of skin-cancer related deaths in North America. Metastatic melanoma is difficult to treat and chemotherapies have limited success. Furthermore, chemotherapies lead to toxic side effects due to nonselective targeting of normal cells. Curcumin is a natural product of <...

Full description

Bibliographic Details
Main Authors: Krishan Parashar, Siddhartha Sood, Ali Mehaidli, Colin Curran, Caleb Vegh, Christopher Nguyen, Christopher Pignanelli, Jianzhang Wu, Guang Liang, Yi Wang, Siyaram Pandey
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Molecules
Subjects:
melanoma
curcumin analog
apoptosis
oxidative stress
drug–drug interaction
tamoxifen
taxol
cisplatin
Online Access:https://www.mdpi.com/1420-3049/24/13/2483

Internet

https://www.mdpi.com/1420-3049/24/13/2483

Similar Items