Co-evolution of transcriptional silencing proteins and the DNA elements specifying their assembly.

Co-evolution of transcriptional regulatory proteins and their sites of action has been often hypothesized but rarely demonstrated. Here we provide experimental evidence of such co-evolution in yeast silent chromatin, a finding that emerged from studies of hybrids formed between two closely related S...

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Bibliographic Details
Main Authors: Oliver A Zill, Devin Scannell, Leonid Teytelman, Jasper Rine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2994660?pdf=render