Overexpression of microRNA-200c predicts poor outcome in patients with PR-negative breast cancer.

Micro-RNAs are small, noncoding RNAs that act as tumor suppressors or oncogenes. MiR-200c is a member of the miR-200 family; it is known to be dysregulated in invasive breast carcinoma. MiR-200c maintains the epithelial-mesenchymal transition and inhibits cell migration and invasion. Recent studies...

Full description

Bibliographic Details
Main Authors: Marie Tuomarila, Kaisa Luostari, Ylermi Soini, Vesa Kataja, Veli-Matti Kosma, Arto Mannermaa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199599?pdf=render