Response of Encapsulated Rat Pancreatic Islets to Hypoxia

Hypoxia contributes to encapsulated pancreatic islet graft failure. To gain insight into the mechanisms that lead to hypoxia-induced graft failure, encapsulated islet function, vitality, and cell replication were assessed after 2 and 5 days of hypoxic (1% O 2 ) and normoxic (20% O 2 ) culture. The m...

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Bibliographic Details
Main Authors: M. de Groot, T. A. Schuurs, P. P. M. Keizer, S. Fekken, H. G. D. Leuvenink, R. Van Schilfgaarde
Format: Article
Language:English
Published: SAGE Publishing 2003-11-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000003771000219