Solid Nanocrystals of Rebamipide Promote Recovery from Indomethacin-Induced Gastrointestinal Bleeding

Solid Nanocrystals of Rebamipide Promote Recovery from Indomethacin-Induced Gastrointestinal Bleeding

Indomethacin (IMC)-induced gastrointestinal (GI) injuries are more common in rheumatoid arthritis (RA) patients than in other IMC users, and the overexpression of nitric oxide (NO) via inducible NO synthase (iNOS) is related to the seriousness of IMC-induced GI injuries. However, sufficient strategi...

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Bibliographic Details
Main Authors: Noriaki Nagai, Ryusuke Sakamoto, Seiji Yamamoto, Saori Deguchi, Hiroko Otake, Tadatoshi Tanino
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
gastrointestinal injury
nanoparticle
rebamipide
indomethacin
rheumatoid arthritis
Online Access:https://www.mdpi.com/1422-0067/20/20/4990

Internet

https://www.mdpi.com/1422-0067/20/20/4990

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