Nicotine-induced Disturbances of Meiotic Maturation in Cultured Mouse Oocytes: Alterations of Spindle Integrity and Chromosome Alignment
We investigated whether nicotine exposure in vitro of mouse oocytes affects spindle and chromosome function during meiotic maturation (M-I and M-II). Oocytes in germinal vesicle (GV) stage were cultured in nicotine for 8 h or for 16 h, to assess effects in M-I and in metaphase II (M-II). The latter...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
European Publishing
2004-09-01
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| Series: | Tobacco Induced Diseases |
| Subjects: | |
| Online Access: | http://www.journalssystem.com/tid/Nicotine-induced-Disturbances-of-Meiotic-Maturation-in-Cultured-Mouse-Oocytes-Alterations-of-Spindle-Integrity-and-Chromosome-Alignment,65878,0,2.html |