Positive regulation of prostate cancer cell growth by lipid droplet forming and processing enzymes DGAT1 and ABHD5

Abstract Background Neoplastic cells proliferate rapidly and obtain requisite building blocks by reprogramming metabolic pathways that favor growth. Previously, we observed that prostate cancer cells uptake and store lipids in the form of lipid droplets, providing building blocks for membrane synthe...

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Bibliographic Details
Main Authors: Ranjana Mitra, Thuc T. Le, Priyatham Gorjala, Oscar B. Goodman Jr.
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-017-3589-6