Bayesian estimation of scaled mutation rate under the coalescent: a sequential Monte Carlo approach

Abstract Background Samples of molecular sequence data of a locus obtained from random individuals in a population are often related by an unknown genealogy. More importantly, population genetics parameters, for instance, the scaled population mutation rate Θ=4N e μ for diploids or Θ=2N e μ for hapl...

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Bibliographic Details
Main Authors: Oyetunji E. Ogundijo, Xiaodong Wang
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1948-6