Rapid Isolation of Functional ex vivo Human Skin Tissue-Resident Memory T Lymphocytes

Rapid Isolation of Functional ex vivo Human Skin Tissue-Resident Memory T Lymphocytes

Studies in animal models have shown that skin tissue-resident memory T (TRM) cells provide enhanced and immediate effector function at the site of infection. However, analyses of skin TRM cells in humans have been hindered by the lack of an optimized isolation protocol. Here, we present a combinator...

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Bibliographic Details
Main Authors: Weijie Du, Daniel Lenz, Ralf Köhler, Erping Zhang, Carla Cendon, Jinchan Li, Mona Massoud, Joachim Wachtlin, Juliane Bodo, Anja E. Hauser, Andreas Radbruch, Jun Dong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
human skin
tissue-resident memory T cells
yield
epitope
collagenase IV
gentle tissue dissociation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.624013/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.624013/full

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