Neuroprotective Effects of Mitochondria-Targeted Plastoquinone in a Rat Model of Neonatal Hypoxic–Ischemic Brain Injury

Neuroprotective Effects of Mitochondria-Targeted Plastoquinone in a Rat Model of Neonatal Hypoxic–Ischemic Brain Injury

Neonatal hypoxia–ischemia is one of the main causes of mortality and disability of newborns. To study the mechanisms of neonatal brain cell damage, we used a model of neonatal hypoxia–ischemia in seven-day-old rats, by annealing of the common carotid artery with subsequent hypoxi...

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Bibliographic Details
Main Authors: Denis N. Silachev, Egor Y. Plotnikov, Irina B. Pevzner, Ljubava D. Zorova, Anastasia V. Balakireva, Mikhail V. Gulyaev, Yury A. Pirogov, Vladimir P. Skulachev, Dmitry B. Zorov
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Molecules
Subjects:
hypoxia–ischemia
mitochondria
mitochondria-targeted antioxidants
plastoquinone
oxidative stress
Online Access:http://www.mdpi.com/1420-3049/23/8/1871

Internet

http://www.mdpi.com/1420-3049/23/8/1871

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