Imidazole and Benzimidazole Modified Half-Sandwich IridiumIIIN-Heterocyclic Carbene Complexes: Synthesis, Anticancer Application, and Organelle Targeting

Imidazole and Benzimidazole Modified Half-Sandwich IridiumIIIN-Heterocyclic Carbene Complexes: Synthesis, Anticancer Application, and Organelle Targeting

Herein, we report the synthesis, characterization and anticancer activity of a series of half-sandwich iridiumIII imidazole and benzimidazole N-heterocyclic carbene (NHC) anticancer complexes, and the general formula of which can be expressed as [(η5-Cpx)Ir(C∧N)Cl]Cl (Cpx: pentamethylcyclopentadieny...

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Bibliographic Details
Main Authors: Xicheng Liu, Yali Han, Xingxing Ge, Zhe Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Chemistry
Subjects:
iridium(III) compounds
anticancer
N-heterocyclic carbene
organelle targeting
imidazole
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00182/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2020.00182/full

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