Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival.

Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival.

<h4>Background</h4>Constitutively active androgen receptor variants (AR-V) lacking the ligand binding domain (LBD) may promote the development of castration-resistant prostate cancer (CRPC). The expression of AR-Vs in the clinically most important metastatic site, the bone, has, however,...

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Bibliographic Details
Main Authors: Emma Hörnberg, Erik Bovinder Ylitalo, Sead Crnalic, Henrik Antti, Pär Stattin, Anders Widmark, Anders Bergh, Pernilla Wikström
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21552559/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21552559/pdf/?tool=EBI

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