Ghrelin, a novel therapy, corrects cytokine and NF-κB-AKT-MAPK network and mitigates intestinal injury induced by combined radiation and skin-wound trauma

Ghrelin, a novel therapy, corrects cytokine and NF-κB-AKT-MAPK network and mitigates intestinal injury induced by combined radiation and skin-wound trauma

Abstract Background Compared to radiation injury alone (RI), radiation injury combined wound (CI) further enhances acute radiation syndrome and subsequently mortality. We previously reported that therapy with Ghrelin, the 28-amino-acid-peptide secreted from the stomach, significantly increased 30-da...

Full description

Bibliographic Details
Main Authors: Juliann G. Kiang, Joan T. Smith, Georgetta Cannon, Marsha N. Anderson, Connie Ho, Min Zhai, Wanchang Cui, Mang Xiao
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cell & Bioscience
Subjects:
Ionizing radiation
Skin wound
Ghrelin
GI
NF-κB
AKT
Online Access:http://link.springer.com/article/10.1186/s13578-020-00425-z

Internet

http://link.springer.com/article/10.1186/s13578-020-00425-z

Similar Items