Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells.

Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells.

Nitration of pollen derived allergens can occur by NO(2) and ozone in polluted air and it has already been shown that nitrated major birch (Betula verrucosa) pollen allergen Bet v 1.0101 (Bet v 1) exhibits an increased potency to trigger an immune response. However, the mechanisms by which nitration...

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Bibliographic Details
Main Authors: Anette C Karle, Gertie J Oostingh, Sonja Mutschlechner, Fatima Ferreira, Peter Lackner, Barbara Bohle, Gottfried F Fischer, Anne B Vogt, Albert Duschl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3279363?pdf=render

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http://europepmc.org/articles/PMC3279363?pdf=render

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