Protective Effect of Gemfibrozil on Hepatotoxicity Induced by Acetaminophen in Mice: the Importance of Oxidative Stress Suppression

Protective Effect of Gemfibrozil on Hepatotoxicity Induced by Acetaminophen in Mice: the Importance of Oxidative Stress Suppression

Purpose: Gemfibrozil (GEM) apart from agonist activity at peroxisome proliferator-activated receptor-alpha (PPAR-α) has antioxidant and anti-inflammatory properties. Accordingly, the present study was designed to investigate the protective effect of GEM on acute liver toxicity induced by acetaminoph...

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Bibliographic Details
Main Authors: Hojatolla Nikravesh, Mohammad Javad Khodayar, Masoud Mahdavinia, Esrafil Mansouri, Leila Zeidooni, Fereshteh Dehbashi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-06-01
Series:Advanced Pharmaceutical Bulletin
Subjects:
Acetaminophen
Oxidative Stress
Gemfibrozil
Hepatoprotective
Mice
Online Access:http://apb.tbzmed.ac.ir/PDF/apb-8-331.pdf

Internet

http://apb.tbzmed.ac.ir/PDF/apb-8-331.pdf

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