Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

Caffeic acid phenethyl ester (CAPE) is a key bioactive ingredient of honeybee propolis and is claimed to have anticancer activity. Since mortalin, a hsp70 chaperone, is enriched in a cancerous cell surface, we recruited a unique cell internalizing anti-mortalin antibody (MotAb) to generate mortalin-...

Full description

Bibliographic Details
Main Authors: Jia Wang, Priyanshu Bhargava, Yue Yu, Anissa Nofita Sari, Huayue Zhang, Noriyuki Ishii, Kangmin Yan, Zhenya Zhang, Yoshiyuki Ishida, Keiji Terao, Sunil C. Kaul, Eijiro Miyako, Renu Wadhwa
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
CAPE
mortalin
internalizing antibody
nanoparticles
enhanced drug delivery
cancer therapy
Online Access:https://www.mdpi.com/2072-6694/12/9/2370

Internet

https://www.mdpi.com/2072-6694/12/9/2370

Similar Items