RBC-NOS-dependent S-nitrosylation of cytoskeletal proteins improves RBC deformability.

RBC-NOS-dependent S-nitrosylation of cytoskeletal proteins improves RBC deformability.

BACKGROUND: Red blood cells (RBC) possess a nitric oxide synthase (RBC-NOS) whose activation depends on the PI3-kinase/Akt kinase pathway. RBC-NOS-produced NO exhibits important biological functions like maintaining RBC deformability. Until now, the cellular target structure for NO, to exert its inf...

Full description

Bibliographic Details
Main Authors: Marijke Grau, Sebastian Pauly, Jamal Ali, Katja Walpurgis, Mario Thevis, Wilhelm Bloch, Frank Suhr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3570529?pdf=render

Internet

http://europepmc.org/articles/PMC3570529?pdf=render

Similar Items