Treatment With Liraglutide Exerts Neuroprotection After Hypoxic–Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway

Treatment With Liraglutide Exerts Neuroprotection After Hypoxic–Ischemic Brain Injury in Neonatal Rats via the PI3K/AKT/GSK3β Pathway

Neonatal hypoxic–ischemic (HI) brain injury is a detrimental disease, which results in high mortality and long-term neurological deficits. Nevertheless, the treatment options for this disease are limited. Thus, the aim of the present study was to assess the role of liraglutide in neonatal HI brain i...

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Bibliographic Details
Main Authors: Shan-shan Zeng, Jun-jie Bai, Huai Jiang, Jin-jin Zhu, Chang-chang Fu, Min-zhi He, Jiang-hu Zhu, Shang-qin Chen, Pei-jun Li, Xiao-qin Fu, Zhen-lang Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neonatal hypoxic-ischemic brain injury
liraglutide
neuroprotection
apoptosis
PI3K/AKT/GSK3β
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00585/full

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https://www.frontiersin.org/article/10.3389/fncel.2019.00585/full

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