PNO1 regulates autophagy and apoptosis of hepatocellular carcinoma via the MAPK signaling pathway

PNO1 regulates autophagy and apoptosis of hepatocellular carcinoma via the MAPK signaling pathway

Abstract Some studies have reported that activated ribosomes are positively associated with malignant tumors, especially in hepatocellular carcinoma (HCC). The RNA-binding protein PNO1 is a critical ribosome rarely reported in human tumors. This study aimed to explore the molecular mechanisms of PNO...

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Main Authors: Zhiqiang Han, Dongming Liu, Lu Chen, Yuchao He, Xiangdong Tian, Lisha Qi, Liwei Chen, Yi Luo, Ziye Chen, Xiaomeng Hu, Guangtao Li, Linlin Zhan, Yu Wang, Qiang Li, Peng Chen, Zhiyong Liu, Hua Guo
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03837-y

Internet

https://doi.org/10.1038/s41419-021-03837-y

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