Discovery of CTCF-sensitive Cis-spliced fusion RNAs between adjacent genes in human prostate cells.

Genes or their encoded products are not expected to mingle with each other unless in some disease situations. In cancer, a frequent mechanism that can produce gene fusions is chromosomal rearrangement. However, recent discoveries of RNA trans-splicing and cis-splicing between adjacent genes (cis-SAG...

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Bibliographic Details
Main Authors: Fujun Qin, Zhenguo Song, Mihaela Babiceanu, Yansu Song, Loryn Facemire, Ritambhara Singh, Mazhar Adli, Hui Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4450057?pdf=render