A Missense Variant Affecting the C-Terminal Tail of UNC93B1 in Dogs with Exfoliative Cutaneous Lupus Erythematosus (ECLE)

A Missense Variant Affecting the C-Terminal Tail of UNC93B1 in Dogs with Exfoliative Cutaneous Lupus Erythematosus (ECLE)

Cutaneous lupus erythematosus (CLE) in humans encompasses multiple subtypes that exhibit a wide array of skin lesions and, in some cases, are associated with the development of systemic lupus erythematosus (SLE). We investigated dogs with exfoliative cutaneous lupus erythematosus (ECLE), a dog-speci...

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Bibliographic Details
Main Authors: Tosso Leeb, Fabienne Leuthard, Vidhya Jagannathan, Sarah Kiener, Anna Letko, Petra Roosje, Monika M. Welle, Katherine L. Gailbreath, Andrea Cannon, Monika Linek, Frane Banovic, Thierry Olivry, Stephen D. White, Kevin Batcher, Danika Bannasch, Katie M. Minor, James R. Mickelson, Marjo K. Hytönen, Hannes Lohi, Elizabeth A. Mauldin, Margret L. Casal
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Genes
Subjects:
<i>canis familiaris</i>
dermatology
immunology
animal model
skin
tlr7
toll-like receptor
syndecan binding protein
syntenin-1
systemic lupus erythematosus
sle
cle
Online Access:https://www.mdpi.com/2073-4425/11/2/159

Internet

https://www.mdpi.com/2073-4425/11/2/159

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