Mitochondrial Regulation of the 26S Proteasome
Summary: The proteasome is the main proteolytic system for targeted protein degradation in the cell and is fine-tuned according to cellular needs. Here, we demonstrate that mitochondrial dysfunction and concomitant metabolic reprogramming of the tricarboxylic acid (TCA) cycle reduce the assembly and...
Main Authors: | Thomas Meul, Korbinian Berschneider, Sabine Schmitt, Christoph H. Mayr, Laura F. Mattner, Herbert B. Schiller, Ayse S. Yazgili, Xinyuan Wang, Christina Lukas, Camille Schlesser, Cornelia Prehn, Jerzy Adamski, Elisabeth Graf, Thomas Schwarzmayr, Fabiana Perocchi, Alexandra Kukat, Aleksandra Trifunovic, Laura Kremer, Holger Prokisch, Bastian Popper, Christine von Toerne, Stefanie M. Hauck, Hans Zischka, Silke Meiners |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-08-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124720310445 |
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