Effector T Helper Cells Are Selectively Controlled During Pregnancy and Related to a Postpartum Relapse in Multiple Sclerosis

Effector T Helper Cells Are Selectively Controlled During Pregnancy and Related to a Postpartum Relapse in Multiple Sclerosis

Background: Multiple sclerosis (MS) patients are protected from relapses during pregnancy and have an increased relapse risk after delivery. It is unknown how pregnancy controls disease-contributing CD4+ T helper (Th) cells and whether this differs in MS patients who experience a postpartum relapse....

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Bibliographic Details
Main Authors: Steven C. Koetzier, Rinze F. Neuteboom, Annet F. Wierenga-Wolf, Marie-José Melief, C. Louk de Mol, Angelique van Rijswijk, Willem A. Dik, Bieke Broux, Ronald van der Wal, Sjoerd A. A. van den Berg, Joost Smolders, Marvin M. van Luijn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
relapse risk
third trimester
serum-related factors
hormones
inflammatory cytokine potential
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.642038/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.642038/full

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