Immunoregulatory mechanisms underlying prevention of colitis-associated colorectal cancer by probiotic bacteria.

BACKGROUND: Inflammatory bowel disease (IBD) increases the risk of colorectal cancer. Probiotic bacteria produce immunoregulatory metabolites in vitro such as conjugated linoleic acid (CLA), a polyunsaturated fatty acid with potent anti-carcinogenic effects. This study aimed to investigate the cellu...

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Bibliographic Details
Main Authors: Josep Bassaganya-Riera, Monica Viladomiu, Mireia Pedragosa, Claudio De Simone, Raquel Hontecillas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3325233?pdf=render