An observational study identifying highly tuberculosis-exposed, HIV-1-positive but persistently TB, tuberculin and IGRA negative persons with M. tuberculosis specific antibodies in Cape Town, South Africa
Background: Mycobacterium tuberculosis (Mtb) infection is inferred from positive results of T-cell immune conversion assays measuring Mtb-specific interferon gamma production or tuberculin skin test (TST) reactivity. Certain exposed individuals do not display T-cell immune conversion in these assays...
Main Authors: | Elouise E. Kroon, Craig J. Kinnear, Marianna Orlova, Stephanie Fischinger, Sally Shin, Sihaam Boolay, Gerhard Walzl, Ashley Jacobs, Robert J. Wilkinson, Galit Alter, Erwin Schurr, Eileen G. Hoal, Marlo Möller |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-11-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396420304291 |
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