Marine Antimicrobial Peptide TP4 Exerts Anticancer Effects on Human Synovial Sarcoma Cells via Calcium Overload, Reactive Oxygen Species Production and Mitochondrial Hyperpolarization

Synovial sarcoma is a rare but aggressive soft-tissue sarcoma associated with translocation t(X;18). Metastasis occurs in approximately 50% of all patients, and curative outcomes are difficult to achieve in this group. Since the efficacies of current therapeutic approaches for metastatic synovial sa...

Full description

Bibliographic Details
Main Authors: Bor-Chyuan Su, Giun-Yi Hung, Yun-Chieh Tu, Wei-Chen Yeh, Meng-Chieh Lin, Jyh-Yih Chen
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Marine Drugs
Subjects:
TP4
Online Access:https://www.mdpi.com/1660-3397/19/2/93