Encapsulation of Risperidone by Methylated β-Cyclodextrins: Physicochemical and Molecular Modeling Studies

Encapsulation of Risperidone by Methylated β-Cyclodextrins: Physicochemical and Molecular Modeling Studies

Risperidone (RSP) is an atypical antipsychotic drug which acts as a potent antagonist of serotonin-2 (5TH2) and dopamine-2 (D2) receptors in the brain; it is used to treat schizophrenia, behavioral and psychological symptoms of dementia and irritability associated with autism. It is a poorly water s...

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Bibliographic Details
Main Authors: Laura Sbârcea, Ionuț-Mihai Tănase, Adriana Ledeți, Denisa Cîrcioban, Gabriela Vlase, Paul Barvinschi, Marinela Miclău, Renata-Maria Văruţ, Cristina Trandafirescu, Ionuț Ledeți
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
risperidone
cyclodextrins
molecular encapsulation
inclusion complex
solubility
Online Access:https://www.mdpi.com/1420-3049/25/23/5694

Internet

https://www.mdpi.com/1420-3049/25/23/5694

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