Upregulation of <i>CASP9 </i>through NF-κB and Its Target MiR-1276 Contributed to TNFα-promoted Apoptosis of Cancer Cells Induced by Doxorubicin

:Under some conditions, nuclear factor-&#954;B (NF-&#954;B) has a pro-apoptotic role, but the mechanisms underlying this function remain unclear. This study demonstrated that NF-&#954;B directly binds to <i>CASP9</i> and miR1276 in tumor necrosis factor &#945; (TNF&#9...

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Bibliographic Details
Main Authors: Fei Zhou, Yun Li, Yisheng Huang, Jian Wu, Qinhan Wu, Hui Zhu, Jinke Wang
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/7/2290