p53 regulates mtDNA copy number and mitocheckpoint pathway

p53 regulates mtDNA copy number and mitocheckpoint pathway

<b>Background: </b> We previously hypothesized a role for mitochondria damage checkpoint (mito-checkpoint) in maintaining the mitochondrial integrity of cells. Consistent with this hypothesis, defects in mitochondria have been demonstrated to cause genetic and epigenetic changes in the n...

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Bibliographic Details
Main Authors: Kulawiec Mariola, Ayyasamy Vanniarajan, Singh Keshav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Journal of Carcinogenesis
Subjects:
Cell cycle
metabolic stress
mitocheckpoint
mitochondrial
mitochondria
mtDNA
p53
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2009;volume=8;issue=1;spage=8;epage=8;aulast=Kulawiec

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http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2009;volume=8;issue=1;spage=8;epage=8;aulast=Kulawiec

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