Effectiveness of porous silicon nanoparticle treatment at inhibiting the migration of a heterogeneous glioma cell population

Effectiveness of porous silicon nanoparticle treatment at inhibiting the migration of a heterogeneous glioma cell population

Abstract Background Approximately 80% of brain tumours are gliomas. Despite treatment, patient mortality remains high due to local metastasis and relapse. It has been shown that transferrin-functionalised porous silicon nanoparticles (Tf@pSiNPs) can inhibit the migration of U87 glioma cells. However...

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Bibliographic Details
Main Authors: Youssef Abdalla, Meihua Luo, Ermei Mäkilä, Bryan W. Day, Nicolas H. Voelcker, Wing Yin Tong
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Nanobiotechnology
Subjects:
Transferrin
Silicon nanoparticles
Glioma
Glioblastoma
Cell migration
aquaporin 9
Online Access:https://doi.org/10.1186/s12951-021-00798-4

Internet

https://doi.org/10.1186/s12951-021-00798-4

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