CD57 expression and cytokine production by T cells in lesional and unaffected skin from patients with psoriasis.

The immunopathogenic mechanisms leading to psoriasis remain unresolved. CD57 is a marker of replicative inability and immunosenescence on CD8+ T cells and the proportion of CD57 expressing CD8+ T cells is increased in a number of inflammatory conditions.We examined the expression of CD57 on T cells...

Full description

Bibliographic Details
Main Authors: Mariana D Batista, Camilla Tincati, Jeffrey M Milush, Emily L Ho, Lishomwa C Ndhlovu, Vanessa A York, Esper G Kallas, Jorge Kalil, Sheila M Keating, Philip J Norris, David Chang, Patrick Unemori, Kieron S Leslie, Toby Maurer, Wilson Liao, Douglas F Nixon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3585296?pdf=render