Hydrogen Sulfide Prevents Advanced Glycation End-Products Induced Activation of the Epithelial Sodium Channel

Advanced glycation end-products (AGEs) are complex and heterogeneous compounds implicated in diabetes. Sodium reabsorption through the epithelial sodium channel (ENaC) at the distal nephron plays an important role in diabetic hypertension. Here, we report that H2S antagonizes AGEs-induced ENaC activ...

Full description

Bibliographic Details
Main Authors: Qiushi Wang, Binlin Song, Shuai Jiang, Chen Liang, Xiao Chen, Jing Shi, Xinyuan Li, Yingying Sun, Mingming Wu, Dan Zhao, Zhi-Ren Zhang, He-Ping Ma
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2015/976848