The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle

The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle

The DNA damage response (DDR) maintains genomic integrity through an elaborate network of signaling pathways that sense DNA damage and recruit effector factors to repair damaged DNA. DDR signaling pathways are usurped and manipulated by the replication programs of many viruses. Here, we review the p...

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Bibliographic Details
Main Authors: Caleb C. McKinney, Katherine L. Hussmann, Alison A. McBride
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Viruses
Subjects:
HPV
papillomavirus
replication
DNA damage response
homologous recombination
keratinocyte
replication foci
DNA repair
partitioning
episome
Online Access:http://www.mdpi.com/1999-4915/7/5/2450

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http://www.mdpi.com/1999-4915/7/5/2450

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