Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data

Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data

The adaptive immune receptor repertoire (AIRR) contains information on an individuals' immune past, present and potential in the form of the evolving sequences that encode the B cell receptor (BCR) repertoire. AIRR sequencing (AIRR-seq) studies rely on databases of known BCR germline variable (...

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Bibliographic Details
Main Authors: Daniel Gadala-Maria, Moriah Gidoni, Susanna Marquez, Jason A. Vander Heiden, Justin T. Kos, Corey T. Watson, Kevin C. O'Connor, Gur Yaari, Steven H. Kleinstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
antibodies
AIRR-seq
somatic hypermutation
allele
BCR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00129/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00129/full

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