RT-qPCR versus Digital PCR: How Do They Impact Differently on Clinical Management of Chronic Myeloid Leukemia Patients?

RT-qPCR versus Digital PCR: How Do They Impact Differently on Clinical Management of Chronic Myeloid Leukemia Patients?

Real-time quantitative PCR (RT-qPCR) is the gold standard to quantify the BCR-ABL1 transcript for molecular response monitoring in chronic myeloid leukemia (CML) patients, and it plays a pivotal role in clinical decision-making process, even if it presents technical limits. Increasing data suggest t...

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Bibliographic Details
Main Authors: Camilla Zanaglio, Simona Bernardi, Lisa Gandolfi, Mirko Farina, Federica Re, Nicola Polverelli, Tatiana Zollner, Alessandro Turra, Enrico Morello, Michele Malagola, Domenico Russo
Format: Article
Language:English
Published: Karger Publishers 2020-10-01
Series:Case Reports in Oncology
Subjects:
chronic myeloid leukemia
digital pcr
minimal residual disease monitoring
rt-qpcr
bcr-abl1
Online Access:https://www.karger.com/Article/FullText/510440

Internet

https://www.karger.com/Article/FullText/510440

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