Folate-Based Radiotracers for PET Imaging—Update and Perspectives

The folate receptor (FR) is expressed in many tumor types, among those ovarian and lung cancer. Due to the high FR affinity of folic acid, it has been used for targeting of FR-positive tumors, allowing specific delivery of attached probes to the malignant tissue. Therefore, nuclear imaging of FR-pos...

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Bibliographic Details
Main Author: Cristina Müller
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Molecules
Subjects:
PET
Online Access:http://www.mdpi.com/1420-3049/18/5/5005