Folate-Based Radiotracers for PET Imaging—Update and Perspectives
The folate receptor (FR) is expressed in many tumor types, among those ovarian and lung cancer. Due to the high FR affinity of folic acid, it has been used for targeting of FR-positive tumors, allowing specific delivery of attached probes to the malignant tissue. Therefore, nuclear imaging of FR-pos...
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Format: | Article |
Language: | English |
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MDPI AG
2013-04-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/18/5/5005 |