Assaying the effect of levodopa on the evaluation of risk in healthy humans.

In humans, dopamine is implicated in reward and risk-based decision-making. However, the specific effects of dopamine augmentation on risk evaluation are unclear. Here we sought to measure the effect of 100 mg oral levodopa, which enhances synaptic release of dopamine, on choice behaviour in healthy...

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Bibliographic Details
Main Authors: Mkael Symmonds, Nicholas D Wright, Elizabeth Fagan, Raymond J Dolan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23844168/?tool=EBI