Translocated duplication of a targeted chromosomal segment enhances gene expression at the duplicated site and results in phenotypic changes in Aspergillus oryzae

Translocated duplication of a targeted chromosomal segment enhances gene expression at the duplicated site and results in phenotypic changes in Aspergillus oryzae

Abstract Background Translocated chromosomal duplications occur spontaneously in many organisms; segmental duplications of large chromosomal regions are expected to result in phenotypic changes because of gene dosage effects. Therefore, experimentally generated segmental duplications in targeted chr...

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Bibliographic Details
Main Authors: Tadashi Takahashi, Masahiro Ogawa, Atsushi Sato, Yasuji Koyama
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Fungal Biology and Biotechnology
Subjects:
Targeted chromosomal duplication
Translocated duplication
Break induced replication
Aspergillus oryzae
Phenotypic change
prtT
Online Access:http://link.springer.com/article/10.1186/s40694-018-0061-6

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http://link.springer.com/article/10.1186/s40694-018-0061-6

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