Glucose depletion in the airway surface liquid is essential for sterility of the airways.

Diabetes mellitus predisposes the host to bacterial infections. Moreover, hyperglycemia has been shown to be an independent risk factor for respiratory infections. The luminal surface of airway epithelia is covered by a thin layer of airway surface liquid (ASL) and is normally sterile despite consta...

Full description

Bibliographic Details
Main Authors: Alejandro A Pezzulo, Jeydith Gutiérrez, Kelly S Duschner, Kelly S McConnell, Peter J Taft, Sarah E Ernst, Timothy L Yahr, Kamal Rahmouni, Julia Klesney-Tait, David A Stoltz, Joseph Zabner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3029092?pdf=render