Negative Staining for COL4A5 Correlates With Worse Prognosis and More Severe Ultrastructural Alterations in Males With Alport Syndrome

Negative Staining for COL4A5 Correlates With Worse Prognosis and More Severe Ultrastructural Alterations in Males With Alport Syndrome

Alport syndrome (AS) is a genetic disorder characterized by progressive hematuric nephropathy with or without sensorineural hearing loss and ocular lesions. Previous studies on AS included mostly children. Methods: To determine the prognostic value of loss of staining for collagen type IV alpha 5 (C...

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Bibliographic Details
Main Authors: Samar M. Said, Mary E. Fidler, Anthony M. Valeri, Brooke McCann, Wade Fiedler, Lynn D. Cornell, Mariam Priya Alexander, Ahmed M. Alkhunaizi, Anne Sullivan, Carl H. Cramer, Marie C. Hogan, Samih H. Nasr
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Kidney International Reports
Subjects:
Alport syndrome
collagen chains staining
electron microscopy
hereditary nephritis
renal biopsy
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024916301358

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http://www.sciencedirect.com/science/article/pii/S2468024916301358

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