Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

Lack of fragile X mental retardation protein (FMRP) causes Fragile X Syndrome, the most common form of inherited mental retardation. FMRP is an RNA-binding protein and is a component of messenger ribonucleoprotein complexes, associated with brain polyribosomes, including dendritic polysomes. FMRP is...

Full description

Bibliographic Details
Main Authors: Femke M.S. de Vrij, Josien Levenga, Herma C. van der Linde, Sebastiaan K. Koekkoek, Chris I. De Zeeuw, David L. Nelson, Ben A. Oostra, Rob Willemsen
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Neurobiology of Disease
Subjects:
Fragile X syndrome
Spines
Dendrite branching
MPEP
Fenobam
Prepulse inhibition of startle
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000715

Internet

http://www.sciencedirect.com/science/article/pii/S0969996108000715

Similar Items