Impact of GLO1 knock down on GLUT4 trafficking and glucose uptake in L6 myoblasts.

Methylglyoxal (MG), a highly reactive α-dicarbonyl metabolite of glucose degradation pathways, protein and fatty acid metabolism, plays an important role in the pathogenesis of diabetic complications. Hyperglycemia triggers enhanced production of MG and increased generation of advanced glycation end...

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Bibliographic Details
Main Authors: Britta Engelbrecht, Bernd Stratmann, Cornelius Hess, Diethelm Tschoepe, Thomas Gawlowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3662699?pdf=render