Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury

Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury

Motor neuron death is supposed to result in primary motor cortex atrophy after spinal cord injury (SCI), which is relevant to poorer motor recovery for patients with SCI. However, the exact mechanisms of motor neuron death remain elusive. Here, we demonstrated that iron deposition in the motor corte...

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Bibliographic Details
Main Authors: Zhou Feng, Lingxia Min, Hui Chen, Weiwei Deng, Mingliang Tan, Hongliang Liu, Jingming Hou
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Redox Biology
Subjects:
Iron overload
Lipid peroxidation
Motor cortex
Ferroptosis
Spinal cord injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721001324

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http://www.sciencedirect.com/science/article/pii/S2213231721001324

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